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Precose (Acarbose) rating

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Precose

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Precose is an oral medication used to control glucose levels in the blood for people with type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus). It slows down the digestion of sugars and starches helping to prevent the rise in blood sugar that usually occurs after meals. The medication is best suited for use in patients over 18 years of age. Read more

Other names for this medication:
Glucobay, Glucar

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Active Ingredient:
Acarbose

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Description

Precose is an anti-diabetic medication with the active ingredient Acarbose, an alpha-glucosidase inhibitor, which is used in the treatment of type 2 diabetes mellitus and is usually followed by a proper diet and exercise program. Acarbose slows down the breakdown of carbohydrates into glucose and other monosaccharides which results in a smaller rise of glucose in the blood. This helps to control blood sugar level in diabetic patients decreasing the chances of getting a heart attack or stroke and preventing kidney damage, blindness, nerve problems, sexual dysfunction, and limb loss.

Indications

Treatment of non-insulin-dependent diabetes mellitus (NIDDM), especially when the results of a restricted diet and other sugar-lowering drugs aren’t satisfactory.

Treatment of gestational diabetes when diet and exercise aren’t enough (off-label use).

MOA (mechanism of action)

Acarbose is an inhibitor of glycoside hydrolases, alpha-glucosidase in the small intestine and alpha-amylase in the pancreas, which digest carbohydrates. Alpha-amylase breaks down complex carbohydrates into oligosaccharides, while alpha-glucosidase hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. By inhibiting these enzymes Acarbose slows down the absorption of sugars and lowers postprandial hyperglycemia.

Dosage

The medication is taken orally with a meal. Precose should be chewed with the first bite of food or swallowed whole with some liquid right before the meal.

Maximum allowed dose: 600 mg a day (200 mg three times a day).

Do not change the dose or stop taking Precose without consulting your doctor first.

To make the treatment more effective follow a proper diet and an exercise program.

Missed dose

If you miss a dose you should take it as soon as you remember about your missing and make sure it’s taken with food. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose to make up for a forgotten one. Do not take Precose between the meals.

Overdose

An excessive dose of Precose, especially taken with food or drinks that contain carbohydrates, may lead to flatulence (wind), stomach pain and diarrhea. If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 20°C and 25°C (68°F and 77°F) away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Precose are:

  • flatulence or wind
  • abdominal pain
  • diarrhea
  • nausea
  • vomiting
  • indigestion
  • allergic reaction, such as rash, redness of the skin, or itching
  • fluid retention (oedema)
  • jaundice
  • inflammation of the liver (hepatitis)
  • a decrease in the number of platelets in the blood (thrombocytopenia)

Do not take antacids (indigestion medicines) for the treatment of these symptoms as they’re unlikely to help. If the symptoms persist more than 2-3 days, especially in the case of diarrhea, immediately contact your doctor.

Side effects occurrence does not only depend on the medication you are taking but also on your overall health and other factors.

Contraindications

Do not take Precose if you’re allergic to Acarbose or any other ingredients in the formulation.

Do not take Precose if you have a severe kidney disorder (creatinine clearance less than 25 mL/min).

Do not take Precose if you suffer from severe hepatic impairment, e.g. liver cirrhosis.

Do not take Precose if you suffer from intestinal obstruction, inflammation or ulceration of the bowel.

Do not take Precose if you have chronic intestinal diseases associated with digestion or absorption disorders or suffer from ailments which may worsen due to the increased gas formation in the intestine, e.g. larger hernias.

Precose can be taken by pregnant women but only under a doctor’s supervision.

Precose is not recommended for breastfeeding women.

Precose is not recommended for children under the age of 18.

Consuming household sugar during the treatment with Precose can lead to severe abdominal discomfort and diarrhea.

Taking Precose with such drugs as thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel-blocking drugs, and isoniazid may lead to a too low blood sugar level.

Taking Precose with Sulfonylureas or Insulin may lead to hypoglycemia and in such cases its dosage must be adjusted accordingly.

Taking digestive containing carbohydrate-splitting enzymes (amylase, pancreatin etc.) and intestinal absorbents (charcoal) may decrease the effect of Precose.

Taking Precose with digoxin decreases the effect of the latter and requires a dosage adjustment.

Q: What is Precose used for?

A: Precose is used to control sugar level in the blood after each meal in order to manage type 2 diabetes mellitus.

Q: How should I take Precose?

A: Precose should be chewed with the first bite of your food or swallowed whole with some liquid right before the meal. The dosage regimen may vary due to the health differences of the patients and it should be determined by a doctor.

Q: Can Precose be taken by pregnant or breastfeeding women?

A: Precose can be taken by pregnant women only under a doctor’s supervision. Precose isn’t recommended for breastfeeding women.

Q: Can Precose be taken by children?

A: Precose is not recommended for patients under the age of 18.

Target Point Shipping Method Tracking Delivery Time Price
Worldwide Shipping

Worldwide Shipping

Registered Mail  Not trackable 14-21 business days USD 15.00 per order
EMS  Trackable, where available 5-9 business days USD 25.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 15.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 25.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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